During the reprogramming of somatic cells back into stem cells, gene regulation is controlled by pioneer transcription factors. These bind to the tightly packaged DNA in order to make it accessible.

A new study developed a mineralized DNA hydrogel that combines immune regulation with sustained bone regeneration. Using ...

A new study has shed light on the challenges of converting one type of specialized cell into another, a process critical for advances in regenerative medicine. Despite recent progress in the field, a ...

Cellular reprogramming is the hottest topic in longevity science, with tech titans like Sam Altman investing in it. It's now ...

Proprietary Synthetic Polynucleotide Platform Accelerates Non-Viral, Footprint-Free Induced Pluripotent Stem Cell Generation Amid Surging Commercialization of iPSC Therapies in Japan ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

To assemble these minuscule structures, researchers first create a scaffold: a long piece of single-stranded DNA with a carefully designed sequence of bases. Then they add hundreds of shorter DNA ...

For those hoping to cure death, and they are legion, a 2016 experiment at the Salk Institute for Biological Studies in San Diego has become liminal — the moment that changed everything. The experiment ...

Researchers at Johns Hopkins University and Texas A&M University have documented at least 522 autosomal sites where DNA methylation patterns pass from parent to offspring without following Mendel’s ...